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10.1093/aje/kwy086 26 MianP.AllegaertK.ConingsS.AnnaertP.TibboelD.PfisterM.et al (2020)

In severe cases, an abscess can form requiring incision and drainage

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The recommended concentration for treating hyperpigmentation ranges from point one to point five percent in serums and point zero five to point two percent in creams and lotions, with higher concentrations providing more intensive treatment for stubborn pigmentation concerns