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These mechanisms could help mitigate the structural and functional disruptions caused by collagen IV mutations in Alport syndrome

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[3] The N-terminal domain contains the glutathione-binding site and is a highly conserved region among all GSTs

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The cell pellet was thawed, homogenized, and lysed in a buffer containing 20 mM HEPES pH 7.5, 50 mM NaCl, 2 mM MgCl 2 , and complete protease inhibitor cocktail tablet (Roche), and the membranes were collected by centrifugation at 40,000 g

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