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CP nephrotoxicity may result in a wide range of manifestations including distal renal tubular acidosis, chronic kidney disease (CKD), defect in urinary concentrating ability, thrombotic microangiopathy, transient proteinuria, glucosuria, hyperuricemia, hypocalcemia, and other electrolyte imbalances, most importantly magnesium and potassium losses (Miller et al., 2010

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Meanwhile, no ION cases were reported with the oral semaglutide formulation used for type 2 diabetes, Rybelsus

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