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Compound 4 (1.94 g, 2.47 mmol), H-Lys-OMe2HCl (0.24 g, 1.03 mmol), PYBOP (1.62 g, 3.10 mmol) and HOBT (0.42 g, 3.10 mmol) were dissolved in DMF (40 mL) under nitrogen atmosphere and ice bath conditions

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Behavioral Support : Consider counseling or support groups to help with emotional eating and stress management

Beta-3 adrenergic receptors are G-protein coupled receptors predominantly expressed in adipose tissue, particularly visceral and brown fat