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No standardized dosing protocol exists for Dihexa in human clinical medicine

This is especially important for researchers working with compounded or lyophilized formulations where waste from expired medication can be significant

However, it may or may not be beneficial cost-wise

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Patients with NF1 possess only a single functional copy of the NF1 gene (e.g., the first hit), with loss of the second copy acting as an oncogenic second hit and thereby allowing constitutive activation of this pathway [9]

This broader activity is being studied for greater weight loss and metabolic effects than GLP1 alone, but it may also change tolerability and monitoring needs