Moreover, the findings that mice with neutrophil-specific Gpx4 haploinsufficiency recapitulate key clinical features of human SLE, including autoantibodies, neutropenia, skin lesions and proteinuria, and that the treatment with a specific ferroptosis inhibitor significantly ameliorates disease severity in lupus-prone mice reveal the role of neutrophil ferroptosis in lupus pathogenesis
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Injecting a contaminated or aggregated peptide can cause injection site abscesses, systemic infection, or immune-mediated reactions
Rat caries models further confirmed that the material inhibits enamel demineralization and exhibits excellent biocompatibility (Zhu et al., 2025)
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Societal changes driven by uptake of GLP-1 weight loss medications The sweeping changes in food preference and appetite brought on by GLP-1RA pharmacotherapies are producing extensive downstream effects that reach beyond the individual, shaping broader cultural, social, and economic landscapes