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The same 2005 trial also examined a combination of 5% Leuphasyl and 5% Argireline applied over 28 days, resulting in an average wrinkle depth reduction of 24.62%, with maximum reductions observed up to 46.53% , indicating a synergistic effect between the two peptides

Partearroyo T, Murillo-Cuesta S, Vallecillo N, et al

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Cells were fixed and permeabilized

In 2010, 29 different variant alleles have been described (Ford & Berg, 2010) and this may be associated with large interindividual variations in thiopurine drug toxicity and therapeutic efficacy

PMCID: PMC11034947