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Healthy nutrition helps support macular pigment, healthy inflammation, antioxidant defenses, mitochondrial function, and overall retinal health

IV administration also introduces risks that oral supplementation does not: Contamination or excessive endotoxin exposure Sterility and compounding failures Infusion reactions Venous irritation or infection Dosing errors Additional cost and clinical complexity The FDA has reported adverse events among patients who received injectable compounded glutathione made with an unsuitable dietary ingredient

Many patients did not stick with the treatment, and there was a small but notable increase in risk for acute pancreatitis

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Reduced glucose metabolism in AD may be a consequence of reduced postsynaptic neurotransmission, since depolarizing agents trigger glucose uptake in the brain and the effect is reduced in AD (60)

doi:10.1093/jn/130.7.1835S