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A GP or specialist can assess whether an individual's medical history, current medications, or underlying conditions make the use of a GLP-1/GIP/glucagon receptor agonist particularly risky

Over the next years, it will be important to understand the effect of the reduced circulating amino-acids with the novel multi-agonists targeting the glucagon receptor on lean muscle mass (especially in populations with obesity and high risk of sarcopenia) as well as on energy expenditure [66]

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