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82 The serum levels of creatinine and blood urea nitrogen were also reduced after EX-4 administration
Some muscle loss can occur during rapid weight reduction, especially with low protein intake
104,105 The activation of GLP-1R may enhance the brains capability to cope with stress by facilitating the release of neurotransmitters and managing the stress response, potentially mitigating both cognitive and emotional challenges related to aging
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However, patients who may be at higher risk for wet age-related macular degeneration, such as older adults, should be aware of the possibility of new visual symptoms. The exact reasons are unknown, but one explanation is that if blood sugar drops too quickly or too sharply in certain patients, this may unexpectedly affect the retina the light-sensitive tissue at the back of the eye, which contains GLP-1 receptors, the authors say