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June 26, 2023

Heterogeneity in response to GLP-1 receptor agonists in type 2 diabetes in real-world clinical practice: insights from the DPV register an IMI-SOPHIA study

Our meta-analysis of 49 murine single-cell datasets revealed that Mtnr1a transcripts were detectable in the lung, whereas Mtnr1b was largely absent ( Supplementary Figure 3A ), whereas in a similar analysis of over 250 human datasets, both Mtnr1a and Mtnr1b were detected ( Supplementary Figure 3B )

The EMBRAZE trial result is a meaningful step

The end result is that less glucose is able to move into the muscle cell and be converted into glycogen

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