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Diabetes Care , 41 (9), 19261937

However, clinical trials are exploring molecularly targeted therapies based on genetic alterations (e.g., MEK inhibitors in NF1-mutant tumors) and immunotherapy approaches such as checkpoint inhibitors

Saroglitazar is a dual agonist of PPAR-/

The SURMOUNT-1 trial showed mean weight reductions of approximately 15.0% (5 mg dose), 19.5% (10 mg dose), and 20.9% (15 mg dose) at 72 weeks

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Last Published 07.01.2026 Effective Date: 07.01.2026 This policy addresses the use of Korsuva (difelikefalin) for the treatment of moderate-to-severe pruritus associated with chronic kidney disease in adults undergoing hemodialysis