Meta-analyses find it improves cognition in mild cognitive impairment and early Alzheimers, with one review putting the benefit at roughly four to twelve weeks per course, longer than a nootropics washout and shorter than a durable structural change, and it usually needs maintenance
High Ferritin Iron Overload/Toxicity As a side rabbit hole, while I had been struggling with low ferritin that was discovered in 2011 and resolved in 2017 (it also flared up in 2020, then again in 2022), ironically, my husband had iron overload that was diagnosed in 2018, and it resolved in 2021 due to some extreme lifestyle changes
For long-term use, it is especially important to have medical oversight and guidance
The Bigger Picture: A Regulatory Thaw
Do I need to have a blood test prior to prove B12 deficiency
This selectivity is particularly important for individuals seeking pure fat reduction rather than body recomposition, those who do not want muscle hypertrophy for aesthetic or functional reasons, athletes in weight-class sports who need fat loss without muscle gain, individuals with contraindications to growth-promoting interventions, and those concerned about cell proliferation effects