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Effect of combined treatment with folic acid, vitamin B6, and vitamin B12 on plasma biomarkers of inflammation and endothelial dysfunction in women

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Participants enrolled in the study were eligible for analysis in both the intent-to-treat (ITT) and PP analysis, with the exception of three participants in the L-Carnitine group that had completed the study out of window ( n = 1) or had protocol deviations ( n = 2) which excluded them from the PP analysis

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Several of these genes were already reduced due to the genotype and thus, aspirin further aggravated their down-regulation (Table 1)