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Retatrutide Clinical Trial Results: The Data Phase 3 TRIUMPH-4 Trial (December 2025) The TRIUMPH-4 Phase 3 study enrolled 445 participants with obesity or overweight who also had knee osteoarthritis
The effects on a breastfeeding infant are unknown, but caution is advised until more research is available
References include the SURMOUNT-1 trial publication (Jastreboff et al., New England Journal of Medicine, 2022), the Mounjaro and Zepbound prescribing information (Eli Lilly, 2024), Liu et al., JAMA Internal Medicine, 2018 (steroid-induced hyperglycemia), and American Diabetes Association Standards of Care, 2024
WADA continues tracking caffeine use patterns in competition, though the substance remains legal at any dose
At JosephCareRX, our team works closely with patients to determine whether Ozempic or a similar GLP1 medication is appropriate based on their medical history, current medications, and glycemic targets