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In scientific literature, this combination has been investigated for coordinated stimulation of GHRH and ghrelin receptor pathways, with human research reporting measurable changes in growth hormone and IGF-1 biomarkers under supervised conditions

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In addition, it was discovered that WA diminished the effects of TNF and TGF on non-tumourigenic MCF-10A cells during EMT as altered EMT markers such as E-cadherin and vimentin in breast cancer cell lines

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These changes protect the peptide from enzymatic breakdown and enhance its binding affinity to GHRH receptors