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You cannot make B12 yourself

Published phase 3 trials including OASIS 1 (Knop et al., 2023) show that even low absolute bioavailability can be clinically meaningful if the drug is potent enough and the dose is calibrated accordingly

This pattern supports both immediate replenishment and a foundation for ongoing B12 status

Occasionally, some may notice mild soreness at the injection site or temporary flushing

A bottle of off-the-shelf bac water that ruined the reconstitution costs ~$10