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Emanuele et al., 2021

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The nanogel design includes poly(N-isopropylacrylamide-coN-[3-(dimethylamino)-propyl]methacrylamide) and is altered with 1-bromododecane to impart hydrophobicity to enhance triclosan loading

We report herein a series of pharmacological and molecular studies in two validated mouse models of PCOS, generated by gestational (PNA) or postweaning (PWA) androgenization, addressing the effects of GLP1-based multi-agonist therapies on metabolic and reproductive traits of PCOS