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Fertility studies in rats have shown no effect on fertility at oral doses of valproate up to 350 mg/kg/day (approximately equal to the MRHD on a mg/m 2 basis) for 60 days

J., Telang F., et al., Profound Decreases in Dopamine Release in Striatum in Detoxified Alcoholics: Possible Orbitofrontal Involvement, Journal of Neuroscience 27, no

This contrasts with testosterone replacement therapy, which does impair fertility and typically must be stopped when trying to conceive

It helps healthcare providers diagnose several health conditions

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Without significant increases in BrdU or Ki67 staining, neoplastic changes in the exocrine compartment would seem unlikely, although endocrine neoplasia would still seem to be a possibility