BPC-157 upregulates VEGF (vascular endothelial growth factor) in tendon tissue, which drives the formation of new capillaries that deliver oxygen and nutrients to a repair site that was effectively starved of vascular support
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VEGF-R2 axis / local angiogenesis BPC-157 upregulates VEGF-R2 (KDR) receptor expression on vascular endothelium at the lesion site, triggering early neoangiogenesis required for tendon and ligament repair (Sikiric 2018, successive reviews)