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When the skin barrier is compromised or when there is an imbalance in how skin cells turn over, the accumulation of keratin becomes more likely

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Furthermore, it has long been believed that biologically active neuropeptides, including -MSH peptides, are amidated with an NH 2 group at the carboxyl terminus and that such amidation is required for both biological activity and stability

Moreover, the reduction in DCUN1D3 expression leads to an impaired antioxidant response in sleep-deprived individuals, thereby increasing their risk of cardiovascular diseases (Shah et al

Lancet 372(9645):12401250 Fineman MS, Mace KF, Diamant M, Darsow T, Cirincione BB, Booker Porter TK et al (2012) Clinical relevance of anti-exenatide antibodies: safety, efficacy and cross-reactivity with long-term treatment