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Yes, but temperature management is critical

When a region is in critical fire danger, power companies tend to shut off power in pre-planned ways in order to prevent electrical equipment from sparking or starting fires

Less urgent but still worth reporting: side effects that do not improve after seven days at any dose level, persistent diarrhea that interferes with daily activities, significant hair thinning (which can occur during rapid weight loss phases and may relate to nutritional deficiencies rather than medication directly), mood changes including increased anxiety or depression, and hair loss patterns that seem disproportionate to weight loss speed

Heart rate increase are also common but usually manageable with medical supervision and dose adjustments

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GLP-1 receptor activation shifts the balance toward suppression