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Substituting these amino acids with alanine resulted in a significant decrease in binding affinity and cAMP production

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Future research should incorporate female animal models to investigate potential sex-specific responses to MAOB inhibition, which will be essential for fully understanding the translational implications of astrocytic GABA dysregulation in PTSD across sexes

PMC9192202 Oxyntomodulin nanofibril self-assembly NaCl neutralizes charge repulsion and drives aggregation