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Approved Immunotherapy Drugs for Gastrointestinal Cancer Several immunotherapy drugs have been approved by regulatory agencies for the treatment of GI cancers, primarily targeting the PD-1/PD-L1 pathway: Pembrolizumab (Keytruda): A PD-1 inhibitor approved for the treatment of: MSI-H* or dMMR* solid tumors, including colorectal cancer and other GI cancers
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