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97.Dall R, Longobardi S, Ehrnborg C, Keay N, Rosen T, Jorgensen JOL, Cuneo RC, Boroujerdi MA, Cittadini A, Napoli R, Christiansen JS, Bengtsson BA, Sacca L, Baxter RC, Basset EE, Sonksen PH, Grp G-S

Prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs), for example, can lead to gastrointestinal issues, kidney damage, and an increased risk of heart problems

in further embodiments, the auris gel formulation contains a viscosity enhancing agent sufficient to provide a viscosity of from about 10 to about 1,000,000 centipoise, from about 500 and 1,000,000 centipoise