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Quality assurance procedures for mass spectrometry untargeted metabolomics

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Excessive ROS production can lead to membrane disintegration, increased lipid peroxidation (accumulation of MDA), reduced membrane fluidity and ion transport, protein cross-linking, and loss of enzyme activity, all of which negatively affect the growth 82

The role of IGF-1 in obesity, cardiovascular disease, and cancer

Thus, our novel findings may pave the way for the discovery and validation of more effective therapeutic strategies to fully eradicate CSCs, ultimately preventing treatment failure and minimizing metastatic dissemination

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