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Recent studies have suggested that I h currents can exert inhibitory effects by increasing the rheobase (minimum current required for firing), thereby reducing firing probability in small-diameter DRG neurons (Liu et al., 2022

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This could have long-term implications for their metabolic health, mobility, and quality of life. Muscle isnt just about tone, its metabolically active tissue

Research also notes increased IFN- and IL-2 with reduced IL-6 and IL-10 levels

3.7 Peroxisome Proliferator-Activated Receptors (PPAR) The only medication in this class that is currently in use is pioglitazone

10.1371/journal.pone.0000391 PLoS One 107 SodtA