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Safety and translational challenges are considerable and must drive clinical application: immune stimulation carries theoretical risk as well as known risk of worsening autoimmune phenomena or inflammatory toxicities, particularly in the setting of active immunosuppression (e.g., newly diagnosed with cytotoxic therapy, on high-dose steroids)

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The list of FDA-approved indications for this class of medication has grown as of late (and currently includes type 2 diabetes, obesity, cardiovascular event risk reduction, obstructive sleep apnea, chronic kidney disease, and metabolic dysfunction-associated steatotic liver disease), and areas of interest for potential future indications are just as long and farreaching

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How much do GLP-1 medications cost under the Medicare GLP-1 Bridge program