Additionally, investigations using cellular models have verified astaxanthin's capacity to activate the Nrf2/ARE pathway and upregulate antioxidant enzymes, providing mechanistic insight into its protective effects against oxidative damage
In addition to its direct antioxidant functions, glutathione (GSH) contributes to the regeneration of other antioxidants, including vitamins C and E, and is involved in critical processes such as iron homeostasis and mitochondrial integrity
Both cross the bloodbrain barrier and have been shown to lower nighttime cortisol by dampening the hypothalamicpituitaryadrenal (HPA) axis, which in turn reduces stressinduced awakenings
This randomized, double-blind, controlled clinical trial was carried out at three teaching hospital-based dermatovenereology clinics in Indonesia
& Ye, Q
doi: 10.1001/jamanetworkopen.2024.49026