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In 10 male subjects, scientists tested the effects of four different meals - a "normally-structured" meal, one with an extra 300 calories of LCTs, another with an extra 300 calories from MCTs, and one with 215 calories from carbs and 75 calories from LCTs

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Key advantages: Oral administration (no injection burden) Scalable manufacturing Potential for combination therapies Broader patient adherence However, these molecules also reintroduce important questions: Will small-molecule receptor activation alter tissue selectivity

Mechanisms of activation of mouse and human enteroendocrine cells by nutrients