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Comparative effectiveness of once-weekly glucagon-like peptide-1 receptor agonists with regard to 6-month glycaemic control and weight outcomes in patients with type 2 diabetes

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In the landmark SURMOUNT-1 trial, published in the New England Journal of Medicine, participants taking 15mg of tirzepatide lost an average of 20.9% of their body weight over 72 weeks

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Nevertheless, there were notable reductions in overall mortality and cardiovascular-related deaths with oral semaglutide compared to a placebo [8]

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