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Antibody formation occurs in some patients, particularly with exenatide, though this rarely has clinical significance
and the Pharmacy Compounding Advisory Committee subsequently voted against adding it to the Category 1/503A bulk drug substances list at its late-2024 meetings, leaving it without a confirmed legal compounding pathway at that time
Conversely, fatigue is a recognized side effect, particularly during initial treatment
There is a wide range of cardioprotective benefits to GLP-1R agonists in addition to their metabolic effects on blood glucose, adiposity, serum lipids, and blood pressure [31]
Pfizer agreed to acquire Metsera for $4.9 billion or $47.50 per share in cash at closing
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