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Who Should Not Use Contrave Contrave is not recommended for patients who: Take chronic opioid medications Have a history of seizures Have uncontrolled anxiety or panic disorders Have uncontrolled hypertension Are pregnant or planning pregnancy These safety considerations help ensure that Contrave is used only in appropriate clinical contexts

limited to 8 doses/month Injection site : Reactions at the injection site with the subcutaneous autoinjector While both compounds share melanocortin-related side effects, PT-141's narrower receptor profile and regulated dosing provide a more controlled risk-benefit profile

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190 AST-120 (spherical carbon adsorbent) in covert hepatic encephalopathy: results of the ASTUTE trial

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