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At the same time, GLP-1 receptor agonists offer documented cardiovascular and renal benefits
Parameters observed in preclinical animal models including quantities used, exposure durations, and inter-dose intervals are not validated for application to human subjects and should not be extrapolated as such
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Interestingly, greater benefits were seen in those with high compared to low homocysteine concentrations at baseline, suggesting the importance of lowering homocysteine levels in prevention of brain atrophy and cognitive decline (91-93)
Am J Physiol Endocrinol Metab (2010) 298:E4958
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