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Faecalibacterium prausnitzii Attenuates CKD via Butyrate-Renal GPR43 Axis

Rehman K, Fatima F, Waheed I, Akash MS

In a recent reinvestigation of the possible presence of GSTP1-1 in human serum, we concluded that it was absent or below the detection limit of the usual spectrophotometric assay, 12 but we did not verify the possible occurrence of oxidized GSTP1-1

GSH depletion-dependent cell death was prevented by selective ferroptosis inhibitors (8 M Fer-1 and 600 nM Lip-1), iron chelator DFO (80 M), as well as autophagic inhibitors Baf-A1 (75 nM) and 3-MA (10 mM)