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LC-MS metabolomic analysis For the LC separation, column A was the Sequant Zic-Hilic (150 mm 4.6 mm, internal diameter (i.d.) 5 m) with a guard column (20 mm 2.1 mm i.d
Persistent fatigue and weakness
found that exogenous -KG mimics glutaminase-mediated ferroptosis, while using a transaminase inhibitor, amino-oxyacetate (AOA), reverses ferroptosis [85, 86]
These proteins collectively fine-tune IGF-1 signaling across tissues, time, and metabolic state
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