Beyond their blood sugar-lowering effects, certain medicationssuch as liraglutide, semaglutide, and tirzepatidehave demonstrated significant effectiveness in promoting weight management, and they have been approved by the Food and Drug Administration (FDA) for long-term obesity treatment
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Retatrutide can plausibly cause heartburn-type symptoms because its GLP-1 receptor activity slows gastric emptying, increasing intra-gastric pressure and the likelihood of acid reflux
GLP-1R is found on various cell types, and salivary gland epithelial cells are included [281]
No diagnostic or therapeutic intent
Less common and long-term GLP-1 drug side effects Not all GLP-1 drug side effects are created equal