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Sieving characteristics of cytokine- and peroxide-induced epithelial barrier leak: Inhibition by berberine

These include both true or oxygen derived free radicals such as superoxide radical (O 2 ),[1] hydroxyl radical (OH) and nitric oxide (NO) radical (NO ) as well as non-oxygen derived radicals such as hydrogen peroxide (H 2 O 2 ) and hypochlorous acid (HOCl);[2] and can start chain reactions resulting in cell damage or death

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PMCID: PMC8035544