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Mechanistically, BPC-157 appears to modulate the nitric oxide (NO) pathway, interact with growth hormone receptors, and influence several molecular pathways involved in angiogenesis, fibroblast migration, and collagen deposition

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Despite this, it is apparent that BPC 157 has huge potential and following further development has promise as a therapy to conservatively treat or aid recovery in hypovascular and hypocellular soft tissues such as tendon and ligaments

The same phenomenon is observed in the 3D spheroids, where, however, the mitochondrial isoform of GPX4 seems to increase following RSL3 treatment, to compensate for the absence of the cytoplasmic isoform