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These results indicate that APR-246 induces p53-independent effects in these cells and that these off-target effects prevent us from detecting any mutant-specific effects even at low doses

LONP1 specifically recognizes and degrades misfolded proteins, oxidatively damaged proteins, protein aggregates, and some critical proteins related to mitochondrial function, thereby maintaining mitochondrial protein homeostasis

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Special attention was placed on comparison of EtOH-treated mice with time-matched controls, to account for the decreases in GSH resulting from food deprivation [34]

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Payne S (2017) Immunity and resistance to viruses