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Acting essentially is what youre saying
In many cases, yes but any switch should be done under medical supervision to ensure proper dosing and safety
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However, it is still a direct myocardial depressant (reduces contractility), and in states in which the sympathetic nervous system is already highly activated (e.g., cardiogenic shock), ketamine retains potential for inducing hypotension
In type 2 diabetes trials, retatrutide showed greater improvements in body weight and HbA1c than reference GLP-1 receptor agonists such as dulaglutide
The parent drug and its metabolites are excreted through bile and urine over 10 to 20 hours (half-life 10 to 20 h for isotretinoin, 17 to 50 h for 4-oxo-isotretinoin) [1]
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