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Insomnia can mean trouble falling asleep, trouble staying asleep, waking too early, or feeling unrefreshed

One study assessed the safety of UroA in humans, finding no adverse effects at dosages ranging from 250 mg to 1000 mg per day administered over a 4-week period

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10.1016/j.jhep.2011.11.009 122 SanyalA

DO NOT combine opioids with benzodiazepines or gabapentinoids to treat pain and DO re-evaluate routinely for deprescribing during chronic use