FDA described insufficient clinical safety information, characterisation concerns and inadequate evidence of effectiveness for its reviewed use
35 Teunisse, S., Bollen, A
Increased energy A significant benefit of vitamin B12 injections is an increase in energy
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Reported Adverse Effects Reported adverse effects from online forums cited in a 2025 systematic review (PMC12313605) included: Anxiety and panic attacks Depression and anhedonia Insomnia Heart palpitations Fatigue and weakness Loss of appetite These anecdotal reports cannot be verified as directly caused by BPC-157 versus contamination, incorrect dosing, or concurrent conditions, but they raise concerns that the peptide might paradoxically worsen mental health in some individuals
Known as the "Body Protection Compound," BPC-157 is a pentadecapeptide derived from human gastric juice