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Only the three programs above passed all four

Lofton explains, Because GLP-1 agonists are gut hormones, the most common side effects are gastrointestinal. She adds, These can include nausea, constipation, diarrhea, reflux symptoms, and sometimes abdominal pain or even vomiting. She cautions that if anyone taking these medications has abdominal pain or vomiting, they should discuss it with their prescriber

Randomized, double-blind, placebo-controlled study of brodalumab, a human antiIL-17 receptor monoclonal antibody, in moderate to severe asthma

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It plays a role in the production of the neurotransmitters serotonin and dopamine, as well, which is why it can strongly impact mood