This setup lets you strip away all the other biological noise and focus only on how the pituitary cells respond
As it goes with many medications, the list is extensive
The synthesis, transportation and metabolism of thyroid hormones can be modified by toxic agents, that can interfere with hormone receptors and allow the beginning of autoimmune processes
HGH is the upstream signal it binds to GH receptors in the liver and other tissues, triggering IGF-1 production as a primary downstream effect
For example, in 2012, a compounded steroid medication that was contaminated with a fungus was administered to patients throughout the country, resulting in over 750 patients contracting fungal infections and more than 60 deaths
The FASEB Journal, 34(2), 32893304