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J Immunol (2004) 172:50915.10.4049/jimmunol.172.1.509 67 EipperSSteinerRLesnerASienczykMPaleschDHalatschMEet alLactoferrin is an allosteric enhancer of the proteolytic activity of cathepsin G

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Thus, it can be hypothesized that the critical importance of Ca 2+ signaling in eryptosis is linked to the expulsion of the nucleus and the organelles (primarily mitochondria) in precursors of erythrocytes during erythropoiesis