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[7] [8] When body fat decreases rapidly, oestrogen levels may fluctuate, potentially leading to irregular periods, lighter bleeding, or temporary amenorrhoea (absence of menstruation)

FMOs: flavin monooxygenases

Regular physical activity consistently contributes to reductions in body weight and fat, facilitates the long-term maintenance of these reductions, and significantly improves metabolic fitness in individuals with obesity (2, 50)