Effective formulations typically contain 0.5-2% GHK-Cu
Once mixed with bacteriostatic water, refrigerate at 28C and use within 28 days for BPC-157 and GHK-Cu, or within 30 days for TB-500 based on stability data from peptide synthesis facilities
Standard protocols suggest 0.25-0.5 mg daily via subcutaneous injection for 4-8 weeks, though optimal dosing for rib injuries has not been established in human clinical trials
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Some studies suggest that unbound GHK (without copper) may be just as effective in skin regeneration, sparking debates about whether copper binding is necessary
Commercial development was discontinued in 2007 after the Phase IIb trial failed to meet its primary endpoint