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Genetic polymorphism associated prefrontal glutathione and its coupling with brain glutamate and peripheral redox status in early psychosis
An excessive shift in the balance would generate reductive stress leading to the protein aggregates and proteotoxicity as was reported in myocardium (Rajasekaran et al
Bardon, Ceder, and Kollberg were the first to demonstrate significantly increased activities of glycolytic enzymes such as hexokinase (HK), phosphofructokinase-1 (PFK1), pyruvate kinase (PKM) and lactate dehydrogenase (LDH) in activated fibroblasts from cystic fibrosis patients (204)
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