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Comparative bioavailability and utilization of particular forms of B12 supplements with potential to mitigate B12-related genetic polymorphisms

2008 May;66(5):250-5

Any issue that can affect the stomach, pancreas or the last 3-4 cm of the small bowel (called the terminal ileum): Stomach: gastrectomy, gastric bypass Pancreas: chronic pancreatitis, removal of the pancreas Terminal ileum: Crohns disease, coeliac disease (an allergy to gluten requiring a very strict gluten-free diet), removal of terminal ileum, ileostomy, radiotherapy to the pelvis (e.g

To minimize environmental exposure, containers should remain tightly sealed when not in use and handled according to established laboratory protocols

Methylcobalamin and hydroxocobalamin tend to be better tolerated than cyanocobalamin, which may cause more allergic or dermatological reactions in sensitive individuals

Hydroxocobalamin lasts longer, meaning you might need fewer shots